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Microbial fermentation has been used in many industries, including medicine, food, energy, chemical industry, agriculture, etc. Process scale-up is a necessary link for fermentation from experimental research to industrial production. Automated parallel bioreactor systems allowing for accurate measurement and control of pH, dissolved oxygen, temperature, as well as the automated addition of nutrients and chemical inducers during growth, have been developed for microbial fermentation. cGMP manufacture of engineered bacterial therapeutics can benefit the health industry. Our licensed facilities are prepared to meet the associated downstream processing and purification in cGMP.