As a reminder, a PICO question is:
PICO:
P-Patient/Population
I-Intervention
C-Comparison
O-Outcome
Example: In patients with SLE is anti-dsDNA or complement levels a better marker of disease activity.
To access great resources (including PubMed) at CNMC:
Intranet main page--> Departments--> The letter L--> Pick Library (Medical)
*Don't forget that searching PubMed through the intranet & library will give you access to more articles than if you just google PubMed. You can also access this at home through VPN.
PubMed
Use MeSH terms to maximize your searching potential. You can find the appropriate MeSH terms for your search here:
http://www.ncbi.nlm.nih.gov/mesh
Don't forget about using clinical queries which will help you to organize the different search hits by type of study (case report, cohort, meta analysis, etc.). Here is the link: http://www.ncbi.nlm.nih.gov/pubmed/clinical
You can also use PubMed for handhelds which allows you to search by directly plugging in the components of your PICO search. This can also be downloaded as an app for your phone for fast article searches!!
Oxford Library
The Oxford Library has amazing links with worksheets to help you systematically analyze an article. The critical appraisal skills programme (CASP) also has many worksheets that you can use to help determine the quality of the article you may be reading.
Critical appraisal for systematic reviews: http://www.cebm.net/critical-appraisal/
CASP worksheets: http://www.casp-uk.net/#!casp-tools-checklists/c18f8